All I have been fighting a battle with vista that has been killing me and many others. There are tons of posts about this issue but i think I have found it and it is an age long problem that has been around for years but we often forget about it.
How many of you have had the infamous I am typeing and it takes a while for the screen to catch up. or outlook hanging and saying "not responding" it seems now that I have found my problems. I was at a point that vista was almost unusable but I kept digging at it. and here is what I found.
First Turn off Aero it seems to improve things considerably. I did find going to classic view helped a ton. But I still had problems with outlook and other things.
Second I went into Anti-virus and excluded scans on ost’s, pst’s, and I excluded the outlook.exe executable.
I restarted my machine and what a surprise I have been functioning back at windows XP levels of speed again it is awesome.